How does Ketamine work?
On a basic neurochemical basis, it is an N-methyl D-aspartate (NMDA) receptor inhibitor. Blocking the NMDA receptor allows for modulation of glutamate (an excitatory neurotransmitter) and ultimately increases levels of Brain-derived neurotrophic factor (BDNF) and mammalian target of rapamycin (m-TOR), which create protein synthesis in neurons.
Many ketamine experts consider this process a “reset” button for the brain, just like you would reset your computer. A ketamine infusion allows the unhealthy neuronal pathways that are constantly “on” in your brain to turn off for a period of time. One can consider all the unhealthy thoughts that continuously occur – such as automatic negative thoughts, obsessive thoughts, anxious thoughts, persistent pain – as these unhealthy pathways. When your brain comes back “on-line”, you can then access the more healthy pathways or loops in your brain.
Simply put, ketamine works by shutting down overactive neurons while improving the healthy function of the existing neurons. In addition, ketamine improves neural connectivity in the brain that enhances daily, healthy brain function. Ketamine helps a patient restore executive control of their thoughts and emotions.
How do I know if Ketamine is Right For Me?
OceanIV requires a $150 in-person office consultation which goes towards your first infusion. This sixty-minute office visit will give ample time for the patient to meet our providers, review risks and benefits of ketamine, answer all questions, and get adequately prepared for the initiation series of ketamine infusions. We are committed to providing each patient with the right tools and resources for success- part of this is presenting alternative therapies that may either compliment or be done instead of ketamine therapy.
Does Ketamine work for All types of depression?
Currently Ketamine is recommended for Treatment Resistant Depression (TRD). TRD is defined as the patient having tried and failed 2-3 types of oral anti-depressant medications.and benefits of ketamine, answer all questions, and get adequately prepared for the initiation series of ketamine infusions. We are committed to providing each patient with the right tools and resources for success- part of this is presenting alternative therapies that may either compliment or be done instead of ketamine therapy.
How Many Treatments will i need?
Ketamine treatment occurs in two steps – “Initiation” and “Maintenance”. The initiation period is different depending on your condition.
Treatment Resistant Depression and Mood Disorders are treated with 6-8 treatments over 3-4 weeks during the initiation phase.
The maintenance period consists of “boosters” – which are typically a single treatment. The first booster is typically scheduled 2-3 weeks after your last initiation infusion. After that, every patient varies, but the average length between boosters is 6-8 weeks.
For patients with mood disorders, OceanIV Progressive Health uses a daily text program to monitor your mood and help decide on timing between infusions.
Migraines are typically treated with one to two treatments during initiation. Most migraine patients need one infusion every 8-12 weeks for maintenance.
Chronic pain infusions are several hours long for several days in a row. The doctor works closely with each patient to tailor an individual schedule that will be most successful. Maintenance infusions for chronic pain are every 2-3 months.
presenting alternative therapies that may either compliment or be done instead of ketamine therapy.
What to know about the day of the infusion?
Please do not have anything to eat four hours prior to your infusion appointment or have anything to drink two hours prior to your appointment. Please also wear Comfortable, loose clothing.You will be greeted by our office staff and asked to fill out a short questionnaire. The doctor will perform a physical exam. The doctor will start an IV and place you on monitors. We will help you get comfortable and then begin the infusion. During your infusion you will have your blood pressure, heart rate, oxygen level and breathing monitored. Typically the infusion lasts one hour, and we monitor you for 15 to 30 minutes after the infusion.
Do I need to stop any of my medication?
No. You should continue to take all your medications as scheduled, including your medications for pain and depression. You may find a decreased need for these meds after your infusion; however, you should work with your doctor to wean off these medications instead of stopping quickly.presenting alternative therapies that may either compliment or be done instead of ketamine therapy.
Who will not recieve infusions?
Any severe hypertension, chest pain, evidence of street drug abuse (cocaine, amphetamines or opiates) or manic symptoms during your physical exam will prohibit you from receiving Ketamine.
Can i drive my self home?
No. Your thinking may be impaired for up to 24 hours, and we require you to have someone to drive you home BEFORE starting the infusion. We also ask that you refrain from operating heavy machinery, avoid strenuous activities, do not watch small children or sign/enter into legal contracts for the next 12 hours.